Can two drugs reboot radioiodine treatment for tough thyroid cancers?
NCT ID NCT04462471
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times
Summary
This early-phase trial tested a combination of two drugs (vemurafenib and copanlisib) in 8 people with advanced thyroid cancer that had stopped responding to standard radioiodine therapy. The goal was to see if the drug combo could make the cancer sensitive to radioiodine again, potentially shrinking tumors. The study focused on finding safe doses and checking for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center @ Commack (Limited Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Limited protocol activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Limited protocol activities)
Rockville Centre, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Limited protocol activities)
Harrison, New York, 10604, United States
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Memorial Sloan-Kettering Cancer Center (All protocol activities)
New York, New York, 10065, United States
Conditions
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