Experimental cell therapy trial offers hope for transplant patients with Treatment-Resistant complications

NCT ID NCT06991361

Summary

This early-stage trial is testing whether a single infusion of specially grown immune cells (EVE-Treg cells) combined with daily low-dose interleukin-2 medication can help control chronic graft-versus-host disease that hasn't responded to standard steroid treatment. The study will enroll 21 children and adults who developed this serious complication after a stem cell transplant for blood cancers. Researchers will primarily assess the safety of this combination approach in patients whose condition hasn't improved with current therapies.

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