One shot to save sight? new trial targets blinding eye disease

NCT ID NCT07215234

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests a single injection into the eye of a new drug (SAR446597) for people with geographic atrophy, a form of advanced age-related macular degeneration that causes blind spots. About 104 participants aged 60 and older will be followed for 2 years, with an optional 3-year extension, to see if the treatment is safe and can slow vision loss. The goal is to control the disease, not cure it, as ongoing management is still needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Associated Retina Consultants - Peoria- Site Number : 8400011

    RECRUITING

    Peoria, Arizona, 85381, United States

  • Austin Clinical Research - Austin - Anderson Mill Road- Site Number : 8400007

    RECRUITING

    Austin, Texas, 78750, United States

  • Cumberland Valley Retina Consultants - Hagerstown- Site Number : 8400003

    RECRUITING

    Hagerstown, Maryland, 21740, United States

  • Investigational Site Number : 0360001

    RECRUITING

    East Melbourne, Victoria, 3002, Australia

  • Investigational Site Number : 0360002

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Investigational Site Number : 0360003

    RECRUITING

    Sydney, New South Wales, 2000, Australia

  • Mid Atlantic Retina - Bethlehem- Site Number : 8400031

    RECRUITING

    Bethlehem, Pennsylvania, 18017-9412, United States

  • Oregon Retina- Site Number : 8400017

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Retina Consultants of Texas - Bellaire- Site Number : 8400019

    RECRUITING

    Bellaire, Texas, 77401, United States

  • Retina Foundation of the Southwest- Site Number : 8400001

    RECRUITING

    Dallas, Texas, 75231, United States

  • Retina Macula Institute of Arizona- Site Number : 8400028

    RECRUITING

    Scottsdale, Arizona, 85255, United States

  • Retina Vitreous Associates of Florida - St. Petersburg- Site Number : 8400002

    RECRUITING

    St. Petersburg, Florida, 33711, United States

  • Retinal Consultants of Texas - San Antonio- Site Number : 8400012

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Texas Retina Associates - Dallas- Site Number : 8400006

    RECRUITING

    Dallas, Texas, 75231, United States

  • The Retina Group of Washington - Chevy Chase- Site Number : 8400009

    RECRUITING

    Chevy Chase, Maryland, 20815, United States

  • University Retina - Lemont- Site Number : 8400005

    RECRUITING

    Lemont, Illinois, 60439, United States

  • Vitreo Retinal Associates - Gainesville- Site Number : 8400004

    RECRUITING

    Gainesville, Florida, 32607, United States

Conditions

Explore the condition pages connected to this study.