New drug shows promise for rare hormone disorder
NCT ID NCT05907291
First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 26 times
Summary
This study tested a new drug called CRN04894 in 38 adults with classic congenital adrenal hyperplasia, a condition where the body can't make certain hormones properly. The goal was to see if the drug could safely lower abnormal hormone levels and reduce the need for high-dose steroids. Participants took the drug for 12 weeks while continuing their usual steroid medications.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Crinetics Study Site
Pasadena, California, 91105, United States
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Crinetics Study Site
Ann Arbor, Michigan, 48109, United States
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Crinetics Study Site
Minneapolis, Minnesota, 55454, United States
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Crinetics Study Site
St Louis, Missouri, 63110, United States
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Crinetics Study Site
Morehead City, North Carolina, 28557, United States
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Crinetics Study Site
Cleveland, Ohio, 44195, United States
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Crinetics Study Site
Philadelphia, Pennsylvania, 19104, United States
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Crinetics Study Site
East Providence, Rhode Island, 02915, United States
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Crinetics Study Site
Córdoba, Córdoba Province, 5000, Argentina
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Crinetics Study Site
Buenos Aires, C1180, Argentina
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Crinetics Study Site
Curitiba, Paraná, 80030-110, Brazil
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Crinetics Study Site
Rio de Janeiro, Rio de Janeiro, 20231-092, Brazil
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Crinetics Study Site
Rio de Janeiro, Rio de Janeiro, 20551-030, Brazil
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Crinetics Study Site
Porto Alegre, Rio Grande do Sul, 90410-000, Brazil
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Crinetics Study Site
Botucatu, São Paulo, 18618-686, Brazil
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Crinetics Study Site
Ribeirão Preto, São Paulo, 14051-140, Brazil
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Crinetics Study Site
São Paulo, São Paulo, 04024-002, Brazil
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Crinetics Study Site
São Paulo, 05403-000, Brazil
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Crinetics Study Site
Munich, Bavaria, 80336, Germany
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Crinetics Study Site
Bangalore, Karnataka, 560054, India
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Crinetics Study Site
Vellore, Tamil Nadu, 632004, India
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Crinetics Study Site
Naples, 80131, Italy
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Crinetics Study Site
Roma, 00161, Italy
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Crinetics Study Site
Rozzano, 20089, Italy
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Crinetics Study Site
Sheffield, South Yorkshire, S10 2RX, United Kingdom
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Crinetics Study Site
Coventry, West Midlands, CV22DX, United Kingdom
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Crinetics Study Site
London, NW1 2PG, United Kingdom
Conditions
Explore the condition pages connected to this study.