Experimental combo for advanced tumors falls short in early trial

NCT ID NCT05571969

First seen Jun 11, 2026 ยท Last updated Jun 11, 2026

Summary

This early-phase study tested a new drug called 2X-121, alone and combined with another drug (dovitinib), in 14 people with advanced solid tumors that had stopped responding to other treatments. The main goal was to find safe doses and check for side effects. The study was terminated early, so no clear conclusions about effectiveness could be drawn.

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Contacts and locations

Locations

  • Carolina BioOncology

    Huntersville, North Carolina, 28078, United States

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.