Tretinoin cream tested for fragile skin in seniors
NCT ID NCT07084116
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether applying tretinoin 0.1% cream nightly to the forearms can reduce skin tears and bruising in people aged 55 and older. Fifteen participants with a history of skin tears and bruising used the cream on one arm and a bland cream on the other for six months. The goal was to see if the treatment lowers tear frequency and improves skin thickness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tretinoin 0.1% cream
What this could lead to
If it works, this could offer a simple cream to reduce skin tears and bruising in older adults with fragile skin.
What could go wrong
This is a small, early-phase study with only 15 people. Results may not apply to everyone, and tretinoin can cause skin irritation.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Palo Alto VA Medical Center
Palo Alto, California, 94304, United States