New pill could ease pain after hip surgery without opioids
NCT ID NCT07543796
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new painkiller called TRD205 for people recovering from hip replacement surgery. About 200 adults will receive either TRD205, a placebo, or an active comparator (celecoxib) to see how well it controls pain and reduces the need for rescue opioids. The goal is to find a safer, effective option for postoperative pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TRD205 tablets
- What this could lead to
- If successful, this could provide a new, non-opioid option for managing pain after hip replacement surgery, potentially reducing reliance on opioids.
- What could go wrong
- This is an early Phase 2 trial with only 200 participants, so results may not apply to everyone. The drug may not prove more effective than existing painkillers or could have unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Third Affiliated Hospital of Southern Medical University
RECRUITINGGuangzhou, Guangdong, 130021, China