New hope for hard-to-treat cancers: experimental drug targets HER2-positive tumors

NCT ID NCT07309770

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called trastuzumab rezetecan in people with advanced solid tumors that have stopped responding to standard therapies. The drug is given every three weeks to 90 participants divided into three groups based on their cancer type. Researchers will measure how many tumors shrink or disappear and track side effects and survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Trastuzumab rezetecan (SHR-A1811), an antibody-drug conjugate

What this could lead to

If successful, this could offer a new treatment option for people with HER2-positive advanced solid tumors who have run out of standard therapies.

What could go wrong

This is an early-phase (Phase II) study with a small number of participants (90). It may not show enough benefit or could have side effects that limit its use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bladder urachal carcinoma cancer extramammary Paget disease urachus cancer urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••