Weekly shot shows promise for boosting growth in kids with dwarfism

NCT ID NCT05598320

First seen Jan 15, 2026 · Last updated May 15, 2026 · Updated 16 times

Summary

This study tested a weekly injection called TransCon CNP in 84 children aged 2 to 11 with achondroplasia, the most common form of dwarfism. The goal was to see if it safely improves growth rate over a year compared to a placebo. After the blinded phase, all children could receive the drug in an open-label extension.

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Contacts and locations

Locations

  • Ascendis Pharma Investigational Site

    Saint Paul, Minnesota, 55102, United States

  • Ascendis Pharma Investigational Site

    Columbia, Missouri, 65212, United States

  • Ascendis Pharma Investigational Site

    Houston, Texas, 77030, United States

  • Ascendis Pharma Investigational Site

    Madison, Wisconsin, 53705, United States

  • Ascendis Pharma Investigational Site

    Parkville, 3052, Australia

  • Ascendis Pharma Investigational Site

    Montreal, H3T 1CS, Canada

  • Ascendis Pharma Investigational Site

    Copenhagen, 2100, Denmark

  • Ascendis Pharma Investigational Site

    Dublin, D01 YC76, Ireland

  • Ascendis Pharma Investigational Site

    Auckland, 1023, New Zealand

  • Ascendis Pharma Investigational Site

    Vitoria-Gasteiz, 1008, Spain

Conditions

Explore the condition pages connected to this study.