New combo therapy shows promise for Hard-to-Treat thyroid cancer

NCT ID NCT02152995

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tested whether the drug trametinib can help radioactive iodine (RAI) work better in people with advanced thyroid cancer that has spread or come back. It included 34 adults whose cancer had a specific gene change (RAS mutation) or no changes in RAS or RAF genes. The goal was to see if trametinib could make cancer cells take up more iodine, potentially slowing tumor growth.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.