Experimental MCL drug trial halted early – what we know
NCT ID NCT06106841
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tested a new drug called TQB3909 in 19 people with mantle cell lymphoma that had returned or stopped responding to treatment. The goal was to find a safe dose and check for side effects. However, the study was terminated early, so we have limited information about how well it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TQB3909 tablets (a BCL-2 inhibitor)
What this could lead to
If successful, this could provide a new treatment option for people with mantle cell lymphoma that has stopped responding to other therapies.
What could go wrong
The trial was terminated early with only 19 participants, so results are very limited. It is unclear if TQB3909 is safe or effective, and it may not work for most patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Cancer Hospital of Harbin Medical University
Harbin, Heilongjiang, 150081, China
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Binzhou Medical University Hospital
Binzhou, Shandong, 256603, China
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Chongqing University Hospital
Chongqing, Chongqing Municipality, 400030, China
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Gansu Provincial Cancer Hospital
Lanzhou, Gansu, 730050, China
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Guangxi Medical University Cancer Hospital
Nanning, Guangxi, 530021, China
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Henan Cancer Hospital
Zhengzhou, Henan, 450000, China
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Heping Hospital Affiliated to Changzhi Medical College
Changzhi, Shanxi, 046000, China
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Institute of Dematology & Blood diseases Hospital
Tianjin, Tianjin Municipality, 300052, China
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Jilin Cancer Hospital
Changchun, Jilin, 130012, China
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Jinzhou Central Hospital
Wuxi, Jiangsu, 530031, China
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Linyi People's Hospital
Linyi, Shandong, 276000, China
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Peking University Third Hospital
Beijing, Beijing Municipality, 100191, China
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Shanghai Huashan Hospital
Shanghai, Shanghai Municipality, 200040, China
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The Affiliated Hospital of Chengde Medical College
Chengde, Hebei, 067000, China
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The Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, 646000, China
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The Affiliated Hospital of Xuzhou Medical University
Nanjing, Jiangsu, 220005, China
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The First Affiliated Hospital Of Soochow University
Suzhou, Jiangsu, 215006, China
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The First Affiliated Hospital of Ningbo University
Ningbo, Zhejiang, 215006, China
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The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, 361003, China
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
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The First Hospital of Jilin University
Changchun, Jilin, 130022, China
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The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
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The Second Affiliated Hospital of Soochow University
Suzhou, Jiangsu, 215004, China
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The Second Hospital of Dalian Medical University
Dalian, Liaoning, 116000, China
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Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, 300040, China
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Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology
Wuhan, Hubei, 430050, China
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Tongji hospital of Tongji University
Shanghai, Shanghai Municipality, 200065, China
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Xinjiang Uygur Autonomous Region People's Hospital
Ürümqi, Xinjiang, 830001, China