New hope for Tough-to-Treat bile duct cancer: targeted pill enters final testing phase

NCT ID NCT05987358

Summary

This study is testing whether TQB3454 tablets can help people with advanced bile duct cancer that has a specific genetic change (IDH1 mutation) and has stopped responding to standard chemotherapy. About 165 participants are randomly assigned to receive either the experimental pill or a placebo (inactive pill) to compare survival time, cancer progression, and side effects. The main goal is to see if this targeted treatment helps people live longer while maintaining their quality of life.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100050, China

  • Lanzhou University Second Hospital

    Lanzhou, Gansu, 730030, China

  • Tangshan People's Hospital

    Tangshan, Hebei, 063001, China

  • Third Affiliated Hospital of Naval Medical University

    Shanghai, Shanghai Municipality, 200433, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, 300181, China

Conditions

Explore the condition pages connected to this study.