New hope for advanced breast cancer: TQB2930 enters phase 3 trial

NCT ID NCT07047365

Recruiting now Disease control Sponsor: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial is testing a new drug called TQB2930, given with chemotherapy, for people with HER2-positive advanced breast cancer who have already tried at least two prior anti-HER2 treatments. The study compares TQB2930 plus chemo to the standard drug trastuzumab plus chemo. About 416 participants will be enrolled to see which combination works better at delaying cancer progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TQB2930 (a bispecific antibody targeting HER2) combined with chemotherapy
What this could lead to: If successful, this could offer a new treatment option for people with HER2-positive advanced breast cancer who have already tried other anti-HER2 therapies.
What could go wrong: This is a phase 3 trial, but it is still experimental. The new drug may not work better than the current standard, and side effects are possible. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HER2-POSITIVE ADVANCED BREAST CANCER

Contacts and locations

Locations

3201 Hospital
NOT_YET_RECRUITING

Hanzhong, Shaanxi, 723000, China
Affiliated Cancer Hospital of Guangxi Medical Universit
NOT_YET_RECRUITING

Nanning, Guangxi, 530028, China
Affiliated Hospital of North Sichuan Medical College
NOT_YET_RECRUITING

Nanchong, Sichuan, 637000, China
Affiliated Zhongshan Hospital Of Dalian University
NOT_YET_RECRUITING

Dalian, Liaoning, 116001, China
AnYang Tumor Hospital
NOT_YET_RECRUITING

Anyang, Henan, 455001, China
Anhui Provincial Hospital( The First Affiliated Hospital of USTC)
NOT_YET_RECRUITING

Hefei, Anhui, 230001, China
Bao Ji Central Hospital
NOT_YET_RECRUITING

Baoji, Shaanxi, 721008, China
Cancer Hospital of Shandong First Medical University (Shandong Cancer Institute,Shandong Cancer Hospital)
NOT_YET_RECRUITING

Jinan, Shandong, 250117, China
Chong Qing University Cancer Hospital
NOT_YET_RECRUITING

Chongqing, Chongqing Municipality, 400030, China
Fuzhou First Generel Hospital Affiliated with Fujian Medical University
NOT_YET_RECRUITING

Fuzhou, Fujian, 350009, China
Gansu Cancer Hospital
NOT_YET_RECRUITING

Lanzhou, Gansu, 730050, China
Ganzhou Cancer Hospital
NOT_YET_RECRUITING

Ganzhou, Jiangxi, 341000, China
Ganzhou People's Hospital
NOT_YET_RECRUITING

Ganzhou, Jiangxi, 341001, China
Guizhou Provincial People's Hospital
NOT_YET_RECRUITING

Guiyang, Guizhou, 550002, China
Hainan General Hospital
NOT_YET_RECRUITING

Haikou, Hainan, 570311, China
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Henan Cancer Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, 450000, China
Hunan Cancer Hospital
NOT_YET_RECRUITING

Changsha, Hunan, 410000, China
Jiamusi Tuberculosis Hospital (Jiamusi Tumor Hospital)
NOT_YET_RECRUITING

Jiamusi, Heilongjiang, 154007, China
JiangSu Cancer Hosipital
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210000, China
Jiangxi Cancer Hospital
NOT_YET_RECRUITING

Nanchang, Jiangxi, 330029, China
Jilin Cancer Hospital
NOT_YET_RECRUITING

Changchun, Jilin, 130000, China
Jingmen People's Hospital
NOT_YET_RECRUITING

Jingmen, Hubei, 448000, China
Liaoning Cancer Hospital & Institute
NOT_YET_RECRUITING

Shenyang, Liaoning, 110043, China
Linyi cancer Hospital
NOT_YET_RECRUITING

Linyi, Shandong, 276000, China
Liuzhou People's Hospital
NOT_YET_RECRUITING

Liuzhou, Guangxi, 545200, China
Mudanjiang Cancer Hospital
NOT_YET_RECRUITING

Mudanjiang, Heilongjiang, 157009, China
Nanjing Drum Tower Hospital
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210031, China
Nanyang Second General Hospital
NOT_YET_RECRUITING

Nanyang, Henan, 47300, China
Ningbo Medical Center Lihuili Hospital
NOT_YET_RECRUITING

Ningbo, Zhejiang, 315000, China
Ningbono.2Hospitai
NOT_YET_RECRUITING

Ningbo, Zhejiang, 315000, China
Peking University Shenzhen Hospital
NOT_YET_RECRUITING

Shenzhen, Guangdong, 518000, China
People's Hospital of Hunan Province
NOT_YET_RECRUITING

Changsha, Hunan, 410005, China
People's Hospital of Ningxia Hui Autonomous Region
NOT_YET_RECRUITING

Yinchuan, Ningxia, 750000, China
Qinghai University Affiliated Hospital
NOT_YET_RECRUITING

Xining, Qinghai, 810001, China
Shandong Provincial Hospital Affiliated to Shandong First Medical University（Shandong Provincial Hospital）
NOT_YET_RECRUITING

Jinan, Shandong, 250021, China
Shanxi Cancer Hospital
NOT_YET_RECRUITING

Taiyuan, Shanxi, 030000, China
Shengjing Hospital of China Medical University
NOT_YET_RECRUITING

Shenyang, Liaoning, 110021, China
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
NOT_YET_RECRUITING

Chengdu, Sichuan, 610072, China
Suining Central Hospital
NOT_YET_RECRUITING

Suining, Sichuan, 629099, China
Sun Yat - sen University Cancer Center
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510060, China
Tangshan People's Hospital
NOT_YET_RECRUITING

Tangshan, Hebei, 063001, China
The Affiiated Cancer Hospital of Guizhou Medical University
NOT_YET_RECRUITING

Guiyang, Guizhou, 550000, China
The Affiliated Hospital of Southwest Medical University
NOT_YET_RECRUITING

Luzhou, Sichuan, 646000, China
The Affiliated Sir Run Run Hospital of Nanjing Medical University
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210000, China
The Central Hospital of Yongzhou
NOT_YET_RECRUITING

Yongzhou, Hunan, 425002, China
The Fifth Medical Center of Chinese People's Liberation Army General Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100071, China
The First Affiliated Hospial of Ningbo University
NOT_YET_RECRUITING

Ningbo, Zhejiang, 315000, China
The First Affiliated Hospital of Bengbu Medical College
NOT_YET_RECRUITING

Bengbu, Anhui, 233060, China
The First Affiliated Hospital of Harbin Medical University
NOT_YET_RECRUITING

Harbin, Heilongjiang, 150000, China
The First Affiliated Hospital of Henan University of Science & Technology
NOT_YET_RECRUITING

Luoyang, Henan, 471000, China
The First Affiliated Hospital of Xinxiang Medical University
NOT_YET_RECRUITING

Xinxiang, Henan, 453100, China
The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITING

Zhengzhou, Henan, 450052, China
The First Hospital of Lanzhou University
NOT_YET_RECRUITING

Lanzhou, Gansu, 730000, China
The First Hospital of Qinhuangdao
NOT_YET_RECRUITING

Qinhuangdao, Hebei, 066000, China
The First People's Hospital of Changde City
NOT_YET_RECRUITING

Changde, Hunan, 415000, China
The Fourth Hospital of Hebei Medical University
NOT_YET_RECRUITING

Shijiazhuang, Hebei, 050035, China
The Second Affiliated Hospital Of Xi'an Jiaotong University (Xibei Hospital)
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710004, China
The Second Affiliated Hospital of Anhui Medical University
NOT_YET_RECRUITING

Hefei, Anhui, 230001, China
The Second Affiliated Hospital of Guangxi University of Science and Technology
NOT_YET_RECRUITING

Liuzhou, Guangxi, 545006, China
The Second Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITING

Wenzhou, Zhejiang, 325000, China
The Second People's Hospital of Yibin City
NOT_YET_RECRUITING

Yibin, Sichuan, 644000, China
The first hospital of Jilin University
NOT_YET_RECRUITING

Changchun, Jilin, 130400, China
Tianjin Cancer Hospital Airport Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300308, China
Tianjin Medical University Cancer Institute & Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300060, China
Weifang People'S Hospital
NOT_YET_RECRUITING

Weifang, Shandong, 261000, China
Xiangya Hospital of Central South University
NOT_YET_RECRUITING

Changsha, Hunan, 410008, China
Xiangyang Central Hospital
NOT_YET_RECRUITING

Xiangyang, Hubei, 441021, China
Xijing Hospital of Air Force Military Medical University
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710032, China
Xinjiang Medical University Affiliated Tumor Hospital
NOT_YET_RECRUITING

Ürümqi, Xinjiang, 830000, China
Xuzhou Central Hospital
NOT_YET_RECRUITING

Xuzhou, Jiangsu, 221009, China
Yuncheng Central Hospital
NOT_YET_RECRUITING

Yuncheng, Shanxi, 044099, China
Yunnan Cancer Hospital
NOT_YET_RECRUITING

Kunming, Yunnan, 650000, China
Zhangjiagang First People's Hospital
NOT_YET_RECRUITING

Suzhou, Jiangsu, 215600, China
Zhangjiajie People's Hospital
NOT_YET_RECRUITING

Zhangjiajie, Hunan, 427000, China

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