New antibody injection takes aim at Hard-to-Treat head and neck cancer
NCT ID NCT07601204
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called TQB2922, given as a shot under the skin, for people with head and neck cancer that has come back or spread. The drug is a special antibody that targets two proteins (EGFR and c-Met) involved in cancer growth. The trial has two parts: first, finding the safest dose in about 128 adults aged 18–75, then checking if the drug works alone or with other treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TQB2922 injection (a bispecific antibody targeting EGFR and c-Met proteins)
- What this could lead to
- If successful, this could point toward a new treatment option for people with head and neck cancer that has returned or spread.
- What could go wrong
- This is an early-phase trial (Phase 1/2) with a small number of participants, so the drug may not prove effective or safe enough for wider use. Side effects are not yet fully known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cancer Hospital Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, 100021, China
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Guangxi Cancer InstituteGuangxi Cancer Hospital
Nanning, Guangxi, 530012, China
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Hubei Cancer Hospital
Wuhan, Hubei, 430079, China
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Hunan Cancer Hospital
Changsha, Hunan, 410013, China
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Shanxi Cancer hospital
Taiyuan, Shanxi, 030000, China
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510060, China
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The First Hospital of China Medical University
Shenyang, Liaoning, 110001, China
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Tianjin Medical University Cancer Institute & Hospital
Tianjin, Tianjin Municipality, 300000, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430023, China
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West China Medical Center,Sichuan Medical University
Chengdu, Sichuan, 610000, China