Myelofibrosis drug combo trial halted early – what we know
NCT ID NCT06245941
First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 21 times
Summary
This study tested a combination of two experimental drugs, TQ05105 and TQB3909, in 21 adults with moderate- to high-risk myelofibrosis, a rare bone marrow disorder. The goal was to find the safest dose and see if the combo could shrink an enlarged spleen by at least 35% after 24 weeks. The trial was terminated early, so final results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hennan Cancer Hospital
Zhengzhou, Henan, 450003, China
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People's Hospital of Tianjin
Tianjin, Tianjin Municipality, 300122, China
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The First Affiliated Hospital Zhejiang University School Of Medicine
Hangzhou, Zhejiang, 310003, China
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The Second People's Hospital of Hefei
Hefei, Anhui, 230012, China
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Xijing Hospital of the Fourth Military Medical University
Xi'an, Shaanxi, 710032, China
Conditions
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