New drug duo aims to shrink enlarged spleens in myelofibrosis patients

NCT ID NCT06122831

First seen Jan 11, 2026 · Last updated May 07, 2026 · Updated 19 times

Summary

This study tests whether a combination of two experimental drugs (TQ05105 and TQB3617) can safely reduce spleen size and improve symptoms in adults with intermediate- or high-risk myelofibrosis, a type of bone marrow cancer. About 92 participants will receive the treatment to find the best dose and measure how well it works. The goal is to control the disease and improve quality of life, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Chengde Medical College

    NOT_YET_RECRUITING

    Chengde, Hebei, 067020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cangzhou People's Hosipital

    NOT_YET_RECRUITING

    Cangzhou, Hebei, 061014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Central Hospital Of Minhang District, Shanghai

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangdong Provincial People's Hospital

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 525000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangxi Zhuang Autonomous Region People's Hospital

    NOT_YET_RECRUITING

    Nanning, Guangxi, 530016, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Cancer Hospital

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Heping Hospital Affiliated to Changzhi Medical College

    NOT_YET_RECRUITING

    Changzhi, Shanxi, 046000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • North China of Science and Technology University Affiliated Hospital

    NOT_YET_RECRUITING

    Tangshan, Hebei, 063000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • People's Hospital of Tianjin City

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300122, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Sixth People's Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200233, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tai'an City Central Hospital

    NOT_YET_RECRUITING

    Tai’an, Shandong, 271099, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Inner Mongolia Medical University

    NOT_YET_RECRUITING

    Hohhot, Inner Mongolia, 010000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xinjiang Medical University

    NOT_YET_RECRUITING

    Ürümqi, Xinjiang, 830011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Harbin

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150010, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Jilin, 130021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Public Hospital of Wuxi

    NOT_YET_RECRUITING

    Wuxi, Jiangsu, 214000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430071, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital Tongji College Huazhong Unizersity of Science And Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430071, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wuhan University Zhongnan Hospital

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430071, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xi 'An Jiaotong University Second Affiliated Hospital

    NOT_YET_RECRUITING

    Xi'an, Shaanxi, 710000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xingtai People's Hospital

    NOT_YET_RECRUITING

    Xingtai, Hebei, 054031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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