3D-Printed ankle bone implant tested in new study

NCT ID NCT06311331

ENROLLING_BY_INVITATION Disease control Sponsor: Restor3D Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a custom 3D-printed device that replaces the talus bone in the ankle. The device is designed for people with severe bone damage from conditions like avascular necrosis or large cartilage defects. Researchers will follow 50 participants for 5 years to see if the implant stays in place and reduces pain without serious complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Total Talus Replacement (TTR) device

What this could lead to

If successful, this device could offer a way to replace a damaged ankle bone, reducing pain and helping people avoid ankle fusion or amputation.

What could go wrong

This is a small, single-arm study with only 50 participants, so results may not apply to everyone. There is a risk of device-related complications or the need for further surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

avascular necrosis osteonecrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OrthoCarolina Research Institute, Inc.

    Charlotte, North Carolina, 28207, United States