Could an immunotherapy drug keep kidney cancer from returning after surgery?

NCT ID NCT06584435

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing whether toripalimab, an immunotherapy drug, can prevent high-risk kidney cancer from coming back after surgery to remove the kidney. About 100 participants will receive the drug every three weeks for up to a year. Researchers will track how long they stay cancer-free and monitor side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

toripalimab (an anti-PD-1 antibody)

What this could lead to

If it works, this could offer a new option to delay or prevent kidney cancer from coming back after surgery.

What could go wrong

This is a small, early-phase study with no comparison group, so results may not be definitive. Side effects from immunotherapy can be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Changyi Quan

    Tianjin, Tianjin Municipality, 300211, China