Chill out: cooling spray tested for nexplanon pain

NCT ID NCT06933381

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a cooling spray (vapocoolant) can reduce the pain of the numbing injection given before placing a Nexplanon birth control implant. About 70 people will be randomly assigned to receive either the cooling spray or a placebo spray before the lidocaine injection. Participants will rate their pain on a scale, and researchers will also ask about satisfaction with pain control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vapocoolant spray (Pain Ease)

What this could lead to

If it works, this could offer a simple, non-drug way to reduce pain during birth control implant insertion.

What could go wrong

This is a small, early-stage trial (70 people) testing a temporary effect. The spray may not meaningfully reduce pain compared to placebo, and results may not apply to other procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Queens Medical Center POB 2 Suite 402

    RECRUITING

    Honolulu, Hawaii, 96813, United States

    Contact

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Queens Medical Center POB1 Clinic 1004

    RECRUITING

    Honolulu, Hawaii, 96813, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Women's Center Queen's North Hawai'i Community Hospital Suite #124 and #120

    NOT_YET_RECRUITING

    Waimea, Hawaii, 96743, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact