Tooth whitening gels put to the hardness test

NCT ID NCT07165366

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether two common tooth whitening agents—a 10% carbamide peroxide gel used at home and a 40% hydrogen peroxide gel used in the dentist's office—change the hardness of tooth enamel. Forty people who needed to have four premolars extracted for orthodontic reasons took part. Researchers measured enamel hardness before and after bleaching to see if either treatment made teeth softer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Carbamide Peroxide 10% and Hydrogen Peroxide 40%
What this could lead to
If successful, this could help dentists choose whitening methods that are less likely to weaken enamel.
What could go wrong
This is a small, completed study measuring only a lab property (hardness), not long-term tooth health or safety. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Universidad Intercontinental

    Mexico City, Tialpan, 14420, Mexico