New hope for rare brain disease: trial tests repurposed drug to stop relapses
NCT ID NCT06452537
Summary
This study is testing if the drug tocilizumab is safe and effective for controlling Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), a rare autoimmune condition that attacks the brain and nerves. It will involve about 102 participants aged 12 and older who have had recent disease relapses. The main goal is to see if tocilizumab can delay or prevent future attacks compared to standard care.
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Contacts and locations
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Locations
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Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, 221006, China
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Anhui Provincial Hospital
Hefei, Anhui, 230001, China
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Beijing Tiantan Hospital, Capital Medical University
Beijing, 100000, China
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Children's Hospital of Soochow University
Suzhou, Jiangsu, 215025, China
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China-Japan Friendship Hospital
Beijing, 100000, China
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Chinese PLA General Hospital
Beijing, 100000, China
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First Hospital of Shanxi Medical University
Taiyuan, Shanxi, 030000, China
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General Hospital of Ningxia Medical University
Yinchuan, Ningxia, 751705, China
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Hebei Children's Hospital
Shijiazhuang, Hebei, 050000, China
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Huashan Hospital, Fudan University
Shanghai, 200000, China
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Ordos Central Hospital
Ordos, Inner Mongolia, 017000, China
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People's Hospital of Xinjiang Uygur Autonomous Region
Ürümqi, Xinjiang Uygur Autonomous Region, 830001, China
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The First Affiliated Hospital of Tsinghua University
Beijing, 100000, China
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The First Affiliated Hospital of Zhengzhou University
Zhenzhou, Henan, China
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The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150086, China
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The Second Hospital of Hebei Medical University
Shijiazhuang, Hebei, 050000, China
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The Second Hospital of Lanzhou University
Lanzhou, Gansu, 73000, China
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The Third Affiliated Hospital of Soochow University
Changzhou, Jiangsu, 213000, China
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Tianjin Children's Hospital
Tianjin, 30052, China
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Tianjin Huanhu Hospital
Tianjin, 300052, China
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Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, 300052, China
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XuanWu Hospital Capital Medical University
Beijing, 100000, China
Conditions
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