New eye implant could slow vision loss from dry AMD

NCT ID NCT07668804

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a biodegradable eye implant called TO-O-1007 for geographic atrophy, a form of advanced dry age-related macular degeneration that causes blind spots. The implant slowly releases medication over 6 months to slow disease progression. About 31 adults aged 50 and older will receive either a low-dose, high-dose, or sham injection to evaluate safety and early effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TO-O-1007 implant

What this could lead to

If successful, this could lead to a treatment that slows vision loss from geographic atrophy with fewer injections.

What could go wrong

This is an early phase trial with only 31 people, so safety and effectiveness are not yet proven. The implant may not slow disease progression or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration Geographic Atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Launceston Eye Doctors

    RECRUITING

    Launceston, Tasmania (tas), 7250, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina & Eye Consultants

    RECRUITING

    Hurstville, New South Wales (nsw), 2220, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sydney Retina Clinic & Day Surgery

    RECRUITING

    Sydney, New South Wales (nsw), 2000, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••