New pill targets genetic weakness in advanced cancers
NCT ID NCT05275478
Summary
This early-stage study is testing a new oral medication called TNG908 in people with advanced solid tumors that have a specific genetic deletion called MTAP. The research aims to find the safest dose and see if the drug shows any signs of fighting the cancer. Up to 192 participants will take the pill daily and can continue as long as they tolerate it and their cancer doesn't worsen.
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Contacts and locations
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Locations
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Carle Cancer Center
Urbana, Illinois, 61801, United States
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Centre Léon Bérard
Lyon, 69373, France
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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EDOG Institut de Cancerologie de l'Ouest
Saint-Herblain, 44805, France
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Florida Cancer Specialists & Research Institute
Lake Mary, Florida, 32746, United States
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Grand Valley Oncology
Grand Junction, Colorado, 81505, United States
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Institut Bergonié
Bordeaux, 33000, France
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Institut Oncopole Claudius Regaud
Toulouse, 31059, France
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Institute Gustav Roussy
Villejuif, 94805, France
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10022, United States
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NEXT Oncology
Fairfax, Virginia, 22031, United States
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NYU Langone Health
New York, New York, 10016, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Sarah Cannon Research Institute at HealthONE
Denver, Colorado, 80218, United States
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Sarah Cannon Tennessee Oncology
Nashville, Tennessee, 37203, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of California Los Angeles
Los Angeles, California, 90095, United States
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University of California San Francisco
San Francisco, California, 94143, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
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