New drug cocktail aims to wipe out aggressive breast cancer before surgery
NCT ID NCT07187674
First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 28 times
Summary
This study tests a combination of two immunotherapy drugs (iparomlimab and tuvonralimab) plus a PARP inhibitor (olaparib) and chemotherapy (paclitaxel) in 20 women with early high-risk triple negative breast cancer that has a specific genetic marker (HRD positive). The goal is to see if this treatment can eliminate all cancer before surgery. Participants will receive six 3-week cycles of the drug combo, then undergo standard breast cancer surgery. The study is not yet recruiting.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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