Brain stimulation may quiet stomach in chronic nausea sufferers

NCT ID NCT07276035

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive brain stimulation technique called TMS can influence stomach activity and reduce nausea in people with chronic nausea and vomiting syndrome. Researchers will map brain areas that connect to the stomach and try different stimulation patterns. Participants will receive TMS while sitting in a chair and will drink water or eat a test meal. The goal is to find the best way to use TMS to ease nausea symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (TMS) device
What this could lead to
If successful, this could point toward a non-drug treatment for chronic nausea by using brain stimulation to calm stomach activity.
What could go wrong
This is an early study exploring brain sites and stimulation patterns, not yet testing a proven treatment. Results may not lead to a reliable therapy, and effects on nausea are uncertain.

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Conditions

The condition(s) this trial relates to.

Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

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