New drug targets tough KRAS cancers in first human trial
NCT ID NCT07204340
Summary
This early-stage trial is testing a new drug called TLN-372, both alone and combined with other cancer treatments, in people with advanced solid tumors driven by a specific KRAS gene mutation. The main goals are to find a safe dose, see how the drug moves through the body, and check for early signs that it can shrink tumors. It is enrolling about 240 adults whose cancer has spread and who have already tried other treatments.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215-5450, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Linear Clinical Research
RECRUITINGPerth, Western Australia, 6009, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10021-3402, United States
Contact Phone: •••-•••-••••
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Peter MacCallum Cancer Centre
RECRUITINGMelbourne, Victoria, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, M5G 1X6, Canada
Contact
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START Madrid_Hospital Universitario HM Sanchinarro_CIOCC
RECRUITINGMadrid, 28050, Spain
Contact
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
Contact Email: •••••@•••••
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Washington University Medical Campus
RECRUITINGSt Louis, Missouri, 63108, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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