New bone graft study aims to improve spine surgery outcomes
NCT ID NCT04073563
First seen Feb 04, 2026 · Last updated May 16, 2026 · Updated 17 times
Summary
This study tests whether a special bone graft (Infuse) helps spine bones fuse better after surgery for degenerative spine disease. About 600 adults with back and leg pain will be randomly assigned to receive the graft or not, and followed for 2 years. The goal is to see if the graft leads to better fusion, less pain, and fewer complications.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Advent Health Altamonte Springs
Altamonte Springs, Florida, 32701, United States
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Advent Health Orlando
Orlando, Florida, 32803, United States
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American Neurospine Institute
Plano, Texas, 75075, United States
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Baystate Medical Center
Springfield, Massachusetts, 01199, United States
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Boulder Neurosurgical Associates and Justin Parker Neurological Institute/E. Lee Nelson
Boulder, Colorado, 80303, United States
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Cedars Sinai Spine Center
Los Angeles, California, 90048, United States
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Chongqing Xinqiao Hospital Second Affiliated Hospital of Army Medical University
Chongqing, 400000, China
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DFW Center for Spinal Disorder
Fort Worth, Texas, 76132, United States
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Foundation for Orthopaedic Research and Education
Tampa, Florida, 33637, United States
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Goodman Campbell Brain and Spine
Carmel, Indiana, 46032, United States
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Hartford Hospital
Hartford, Connecticut, 06106, United States
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Hospital for Special Surgery
New York, New York, 10021, United States
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Indiana Spine Group
Carmel, Indiana, 46032, United States
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Lahey Hospital & Medical Center
Burlington, Massachusetts, 01805, United States
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Mayfield Brain and Spine Clinic
Cincinnati, Ohio, 45209, United States
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Mayo Clinic
Phoenix, Arizona, 85054, United States
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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Mayo Clinic
Rochester, Minnesota, 55901, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Health Services
Laguna Hills, California, 92653, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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Orlando Health
Orlando, Florida, 32806, United States
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OrthoIndy Northwest Office
Indianapolis, Indiana, 46278, United States
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Peking University Third Hospital
Beijing, China
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Penn State-Hershey
Hershey, Pennsylvania, 17033, United States
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Rothman Institute
Philadelphia, Pennsylvania, 19107, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Saint Thomas for Specialty Surgery
Nashville, Tennessee, 37203, United States
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Semmes Murphey
Memphis, Tennessee, 38120, United States
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Swedish Neuroscience
Seattle, Washington, 98122, United States
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Tennessee Orthopaedic Alliance
Nashville, Tennessee, 37209, United States
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The Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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University of Arizona
Tucson, Arizona, 85724, United States
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University of California Davis Medical Center
Sacramento, California, 95816, United States
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University of California Irvine
Irvine, California, 92617, United States
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University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
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University of Iowa Hospitals and Clinic
Iowa City, Iowa, 52242, United States
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University of Michigan Health System
Ann Arbor, Michigan, 48109, United States
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University of Virginia - Clinical Trial Office
Charlottesville, Virginia, 22904, United States
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University of Virginia - Health System
Charlottesville, Virginia, 22908, United States
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Vail-Summit Orthopaedics and Neurosurgery
Vail, Colorado, 81657, United States
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West China Hospital of Sichuan University
Chengdu, China
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West Virginia University, 1 Medical Center Drive
Morgantown, West Virginia, 26506, United States
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William Beaumont Hospital
Royal Oak, Michigan, 48073, United States
Conditions
Explore the condition pages connected to this study.