Weight-Loss shot may help reverse uterine cancer without surgery
NCT ID NCT07349641
First seen Jan 26, 2026 · Last updated May 15, 2026 · Updated 17 times
Summary
This study tests whether adding a weekly tirzepatide injection (a weight-loss drug) to a levonorgestrel IUD (Mirena) can make early-stage endometrial cancer or precancer disappear in overweight or obese women. About 55 women will receive both treatments for 26 weeks. The goal is to avoid hysterectomy by using the IUD to deliver hormones directly to the uterus while tirzepatide helps with weight loss, which may improve outcomes.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ENDOMETRIAL ATYPICAL HYPERPLASIA/ENDOMETRIOID INTRAEPITHELIAL NEOPLASIA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Lyndon Baines Johnson General Hospital
Houston, Texas, 77026-1967, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Northwestern University
Chicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
Explore the condition pages connected to this study.