Could your own tumor cells beat melanoma? new trial tests immune cell therapy

NCT ID NCT05098184

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a therapy made from a patient's own tumor-fighting immune cells (TILs) for advanced melanoma. Doctors take TILs from a tumor sample, grow them in the lab, and infuse them back after a short chemotherapy course. The study aims to see if this approach is safe and can shrink tumors in 50 people who have not responded to standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tumor-infiltrating lymphocytes (TILs)

What this could lead to

If successful, this could offer a new treatment option for advanced melanoma patients who have run out of standard therapies.

What could go wrong

This is a very early, small trial (50 people) focused on safety. The treatment may not shrink tumors, and side effects from the lymphodepletion regimen can be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Tenth People's Hospital

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••