New drug shows promise for bulging eyes condition

NCT ID NCT06021054

Summary

This study tested whether a new drug called veligrotug could safely reduce eye bulging and other symptoms in people with chronic thyroid eye disease. 188 participants received either the drug or a placebo through IV infusions over 12 weeks. Researchers measured changes in eye protrusion, double vision, and overall eye inflammation to determine if the treatment was effective.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advancing Research International, LLC

    Los Angeles, California, 90023, United States

  • Akdeniz University Medical Faculty Hospital

    Antalya, 07059, Turkey (Türkiye)

  • Amy Patel Jain, MD

    Newport Beach, California, 92660, United States

  • Bascom Palmer Eye Institute - Ophthalmology - Miami

    Miami, Florida, 33136, United States

  • Baylor College of Medicine (BCM) - Ophthalmology

    Houston, Texas, 77030, United States

  • Budapest Retina Intezet

    Budapest, H-1133, Hungary

  • CH Nice

    Nice, 06000, France

  • CHU Angers

    Angers, 49033, France

  • CHU de Bordeaux - Hôpital Saint-André

    Bordeaux, 33000, France

  • Centre Hospitalier Universitaire De Nantes - G. R. Laennec

    Nantes, 44093, France

  • Centro de Oftalmologia Barraquer (Barraquer Ophthalmology Centre)

    Barcelona, 08021, Spain

  • Centrum Medyczne Piasta 47 sp. z o.o.

    Wałbrzych, 58-304, Poland

  • Centrum Medyczne Pulawska Sp. z o.o.

    Piaseczno, 05-500, Poland

  • Charité - Universitätsmedizin Berlin KöR

    Berlin, 13353, Germany

  • Cockerham Eye Consultants, PC

    San Diego, California, 92108, United States

  • Complexo Hospitalario Universitario de Santiago-Hospital Médico-Cirúrxico de Conxo

    A Coruña, 15706, Spain

  • Department of Ophthalmology, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Family Eye Physicians, Ltd

    Oak Lawn, Illinois, 60453, United States

  • Ganglion Orvosi Kozpont

    Pécs, H-7621, Hungary

  • Gazi University Medical Faculty Hospital

    Ankara, 06500, Turkey (Türkiye)

  • Guy's and St. Thomas NHS Trust

    London, SE1 7EH, United Kingdom

  • Hacettepe Universitesi Tip Fakultesi

    Ankara, 06230, Turkey (Türkiye)

  • Harborview Medical Center

    Seattle, Washington, 98104, United States

  • Hospital La Arruzafa

    Córdoba, 14012, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Virgen De La Macarena

    Seville, 41009, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • Hospital Universitario Y Politécnico La Fe

    Valencia, 46026, Spain

  • Hospital Unviersitario Miguel Servet

    Zaragoza, 50009, Spain

  • Imperial College Healthcare NHS Trust - Western eye Hospital

    London, NW1 5QH, United Kingdom

  • Kahana Oculoplastic and Orbital Surgery

    Livonia, Michigan, 48152, United States

  • Marmara University Faculty of Medicine

    Istanbul, 34854, Turkey (Türkiye)

  • Massachusetts Eye and Ear

    Boston, Massachusetts, 02114, United States

  • Michigan State University, Department of Neurology

    East Lansing, Michigan, 48824, United States

  • Moorfield's Eye Hospital

    London, EC1V 2PD, United Kingdom

  • Neuro Eye Clinical Trials

    Houston, Texas, 77074, United States

  • North Shore Private Hospital

    Saint Leonards, New South Wales, 2065, Australia

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oculomedica Sp. z o.o.

    Bialystok, 85-157, Poland

  • Ophthalmic Consultants of Boston

    Boston, Massachusetts, 02189, United States

  • Optimum Profesorskie Centrum Okulistyki Sp. z o.o.

    Gdansk, 80-809, Poland

  • Pecsi Tudomanyegyetem Klinikai Kozpont Szemeszeti Klinika

    Pécs, H-7623, Hungary

  • Rutgers - New Jersey Medical School

    Newark, New Jersey, 07103, United States

  • Sarasota Retina Institute

    Sarasota, Florida, 34239, United States

  • Stanford Byers Eye Institute

    Palo Alto, California, 94303, United States

  • Steven Leibowitz, MD.

    Las Vegas, Nevada, 89144, United States

  • The Center for Eye and Facial Plastic Surgery

    Somerset, New Jersey, 08873, United States

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust

    Newcastle, NEI 4LP, United Kingdom

  • USC Roski Eye Institute

    Los Angeles, California, 90089, United States

  • University Hospital Southampton NHS Foundation Trust

    Southampton, SO16 6YD, United Kingdom

  • University Medical Center Freiburg

    Freiburg im Breisgau, 79106, Germany

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Universitätsklinikum Essen AöR

    Essen, 45122, Germany

  • Universitätsmedizin Göttingen

    Göttingen, 37075, Germany

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    Bialystok, 15-276, Poland

  • Washington University School of Medicine in St Louis - Ophthalmology

    St Louis, Missouri, 63110, United States

  • Wills Eye Hospital

    Philadelphia, Pennsylvania, 19107, United States

Conditions

Explore the condition pages connected to this study.