Tiny study: black seed oil changes gut bugs

NCT ID NCT07450807

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether thymoquinone, the main active compound in black seed oil, changes the types of bacteria living in the human gut. Eight healthy adults took black seed oil capsules for 20 days and gave stool samples at five time points. The goal was to see if the oil could help gut healing after surgery, but this was just an early, small study to check for changes in gut bacteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Thymoquinone (from black seed oil)

What this could lead to

If this works, it could point toward using black seed oil to support gut health, especially after surgery.

What could go wrong

This was a very small study (8 people) in healthy adults, with no control group. Results may not apply to sick people or lead to any treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jena University Hospital

    Jena, Thuringia, 07747, Germany