New drug aims to tame dangerous heart rhythms in genetic disorder
NCT ID NCT07277582
First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 26 times
Summary
This study tests an experimental drug, THRV-1268, in 64 people with Long QT Syndrome Type 2 (LQTS 2), a genetic heart condition that can cause dangerous rhythms and sudden cardiac arrest. Participants take the drug twice daily for up to 6 weeks to see if it safely shortens the QT interval, a measure of heart electrical recovery. The goal is to find the best dose that reduces risk without serious side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Heart Center Clinical Research Program | MGH
RECRUITINGBoston, Massachusetts, 02114, United States
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Honor Health Research and Innovation Institute
RECRUITINGScottsdale, Arizona, 85258, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Illinois Chicago
RECRUITINGChicago, Illinois, 60612, United States
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Wilmington Health
RECRUITINGWilmington, North Carolina, 28401, United States
Conditions
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