Scientists hunt for genetic clues in chest cancers

NCT ID NCT00242723

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 39 times

Summary

This study enrolls people with lung, esophageal, or other chest cancers to collect tumor tissue, normal tissue, blood, and urine samples. Researchers will analyze these samples for genetic and epigenetic changes that may affect how the disease progresses. The goal is to better understand these cancers and identify patients who might benefit from future treatment trials at the National Cancer Institute.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new treatments for lung, esophageal, and other chest cancers by identifying key genetic changes.

What could go wrong

This is an observational study, not a treatment trial. It collects samples for research, so there is no direct benefit to participants. Results may take years to influence patient care.

Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms lung cancer lung carcinoma lung neoplasm malignant pleural mesothelioma Mesothelioma, Malignant neoplasm of chest wall neoplasm of mediastinum thoracic cancer thymic carcinoma thymoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.