Freeze-and-Heat attack: could a new device boost liver cancer treatment?
NCT ID NCT07596134
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a special thermal therapy (which freezes and heats tumors) to standard targeted therapy and immunotherapy can help people with advanced liver cancer that cannot be removed by surgery. About 166 participants will be randomly assigned to receive either the combo or standard drugs alone. The main goal is to see if the combo delays cancer growth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Multimodal Thermal Therapy (a device that freezes and heats tumors to destroy them)
- What this could lead to
- If successful, this combination could improve tumor shrinkage and delay cancer progression for people with advanced liver cancer who cannot have surgery.
- What could go wrong
- This is an early-stage trial with only 166 participants, so results may not apply to everyone. The added procedure carries risks like bleeding or infection, and the benefit over standard therapy is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Huaihe Hospital of Henan University
Kaifeng, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang Provinece, China
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Fourth Affiliated Hospital, Zhejiang University School of Medicine
Yiwu, Zhejiang Provinece, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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