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Could a tea compound replace your morning coffee?

NCT ID NCT07376564

Symptom relief Sponsor: Titch Madzima Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested theacrine, a stimulant found in some teas, at higher doses than before. Nineteen healthy adults who regularly consume caffeine took different doses to see how it affected their blood pressure, heart rate, and mental focus. The goal was to see if theacrine could be a safer alternative to caffeine for people who want to avoid jitters or heart issues.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
theacrine
What this could lead to
If it works, theacrine could become a caffeine alternative for people who want a stimulant with fewer side effects.
What could go wrong
This is a small, early study with only 19 people, so results may not apply widely. High doses might still cause side effects like jitters or blood pressure changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Started

Aug 2023

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- habitual caffeine consumer (≥2 days/week) Exclusion Criteria: * existing heart disease or conditions (cardiovascular and/or heart disease, stroke, diabetes hypertension, tachycardia) * a smoker * allergy to caffeine or Theacrine * caffeine sensitivity (negative symptoms such as jitters after consuming low doses) * pregnant * on heart or blood pressure medication

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive performance in healthy volunteers Hemodynamic measure

Contacts and locations

Locations

  • Department of Exercise Science, Koury Athletics Center at Elon University

    Elon, North Carolina, 27244, United States

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