New drug trial targets rare, painful joint tumors

NCT ID NCT05804045

Summary

This study is testing an oral drug called ABSK021 for adults with a rare, non-cancerous joint tumor called TGCT that cannot be fully removed by surgery. The main goal is to see if the drug shrinks tumors and improves symptoms like pain and stiffness compared to a placebo. About 90 participants will receive either the drug or a placebo for 24 weeks, followed by an option for all to receive the drug.

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Contacts and locations

Locations

  • Beijing Jishuitan Hospital

    Beijing, China

  • Duke University Medical Center

    Durham, California, 27710, United States

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    Milan, Italy

  • Fred Hutchinson Cancer Center

    Seattle, Washington, 98109, United States

  • Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, China

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • Hunan Provincial People's Hospital

    Changsha, Hunan, China

  • IRCCS Istituto Ortopedico Rizzoli

    Bologna, Italy

  • Leiden University Medical Center

    Leiden, 2333, Netherlands

  • Liaoning Cancer Hospital&Institute

    Shenyang, Liaoning, China

  • Maria Sklodowska-Curie National Research Institute of Oncology

    Warsaw, Poland

  • McGill University Health Center

    Montreal, Canada

  • Nanjing Drum Tower hospital

    Nanjing, Jiangsu, China

  • Ospedale di Prato

    Prato, Italy

  • Peking University People's Hospital

    Beijing, Beijing Municipality, China

  • Precision NextGen Oncology

    Beverly Hills, California, 90212, United States

  • Princess Margaret Cancer Center

    Toronto, Canada

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

  • Shanghai General Hospital

    Shanghai, Shanghai Municipality, China

  • The Affiliated Hospital of Guizhou Medical University

    Guiyang, Guizhou, China

  • The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture

    Enshi, Hubei, China

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, Anhui, China

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, China

  • The First Affiliated Hospital of Jinan University

    Guangzhou, Guangdong, China

  • The First Affiliated Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, China

  • The First Affiliated Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, China

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

  • The Second Hospital of Shanxi Medical University

    Taiyuan, Shanxi, China

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan, China

  • The University of Texas M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China

  • Weifang People's Hospital

    Weifang, Shandong, China

  • West China Hospital Sichuan University

    Chengdu, Wuhan, China

  • Xi'an Honghui Hospital

    Xi’an, Shanxi, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.