New combo targets Hard-to-Treat breast cancer in early trial

NCT ID NCT05128734

First seen Jan 05, 2026 · Last updated May 06, 2026 · Updated 17 times

Summary

This study tests whether adding the targeted drug olaparib to the chemotherapy temozolomide helps control a specific type of triple-negative breast cancer that has spread or cannot be removed by surgery. About 40 adults with a genetic marker called MGMT methylation will be randomly assigned to receive temozolomide alone or with olaparib. The main goal is to see how many patients have their tumors shrink or stay stable.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arthur J.E. Child Comprehensive Cancer Centre

    Calgary, Alberta, T2N 5G2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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