New drug trial aims to tame debilitating Muscle-Weakening disease

NCT ID NCT06456580

Recruiting now Disease control Sponsor: Vor Biopharma Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called telitacicept to see if it can safely reduce symptoms and improve daily life for adults with generalized myasthenia gravis (gMG), an autoimmune disease that causes severe muscle weakness. About 180 participants will be randomly assigned to receive either the drug or a placebo for 24 weeks, followed by an extended period where all participants can receive the drug. The main goal is to see if the drug helps patients perform daily activities more easily by reducing their disease symptoms.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Allied Biomedical Research Institute (ABRI)
RECRUITING

Miami, Florida, 33155, United States
Aversi Clinic - Central Branch
RECRUITING

Tbilisi, 0160, Georgia
Azienda Ospedaliera - Universitaria Sant' Andrea
RECRUITING

Rome, 00189, Italy
Azienda Ospedaliera Universitaria - Università degli Studi della Campania Luigi Vanvitelli
RECRUITING

Naples, 80131, Italy
Azienda Ospedaliera Universitaria Federico II
RECRUITING

Naples, 80131, Italy
Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli
RECRUITING

Naples, 80131, Italy
Center for Neurological Disorders, S.C. - Greenfield - Gamma Therapeutic Center
RECRUITING

Greenfield, Wisconsin, 53228, United States
Centrum Medyczne Hope Clinic
RECRUITING

Lublin, Lubusz Voivodeship, 20-701, Poland
Centrum Medyczne Neuroprot
RECRUITING

Warsaw, Masovian Voivodeship, 01-684, Poland
Clinirem - Lublin
RECRUITING

Lublin, Lublin Voivodeship, 20-064, Poland
Concord Repatriation General Hospital
RECRUITING

Concord, New South Wales, 2139, Australia
Fakultni Nemocnice Brno
RECRUITING

Brno, South Moravian, 625 00, Czechia
Fakultni Nemocnice Ostrava
RECRUITING

Ostrava-Poruba, Moravian-Silesian, 708 54, Czechia
Fondazione Istituto San Raffaele - G. Giglio Di Cefalu
RECRUITING

Cefalù, Palermo, 90015, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Rome, 00168, Italy
Fundación Scherbovsky
RECRUITING

Mendoza, M5500AXR, Argentina
Gold Coast University Hospital
RECRUITING

Southport, Queensland, 4215, Australia
Groupe Hospitalier Pellegrin
RECRUITING

Bordeaux, Gironde, 33076, France
Hokkaido University Hospital
RECRUITING

Sapporo, Hokkaido, 060-8648, Japan
Hospital General Universitario Dr. Balmis
RECRUITING

Alicante, 03010, Spain
Hospital General de Agudos José María Ramos Mejía
RECRUITING

Ciudad Autónoma de Buenos Aires, Buenos Aires, C1221ADC, Argentina
Hospital Italiano de Buenos Aires
RECRUITING

Ciudad Autónoma de Buenos Aires, Buenos Aires, C1199ABB, Argentina
Hospital São Lucas da PUCRS
RECRUITING

Porto Alegre, Rio Grande do Sul, 90619-900, Brazil
Hospital Universitari Mútua Terrassa
RECRUITING

Terrassa, Barcelona, 08221, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitari i Politècnic La Fe
RECRUITING

Valencia, 46026, Spain
Hospital Universitario de Basurto
RECRUITING

Bilbao, Biscay, 48013, Spain
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto
RECRUITING

Ribeirão Preto, São Paulo, 14051-140, Brazil
Houston Methodist Neurological Institute
RECRUITING

Houston, Texas, 77030, United States
Hôpital Pasteur
RECRUITING

Nice, Alpes-Maritimes, 06001, France
INECO Neurociencias Oroño
RECRUITING

Rosario, Santa Fe Province, S2000TP, Argentina
IRCCS Fondazione Casa Sollievo della Sofferenza SG Rotondo
RECRUITING

San Giovanni Rotondo, Foggia, 71013, Italy
Instituto de Neurologia de Curitiba
RECRUITING

Curitiba, Paraná, 81210-310, Brazil
Istituto Neurologico Casimiro Mondino
RECRUITING

Pavia, 27100, Italy
Juntendo University Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8431, Japan
Kobe University Hospital
RECRUITING

Kobe, Hyōgo, 650-0017, Japan
Krakowska Akademia Neurologii Sp. z o.o.
RECRUITING

Krakow, Lesser Poland Voivodeship, 31-505, Poland
Kyushu University Hospital
RECRUITING

Fukuoka, 812-8582, Japan
MINKSneuro s.r.o. - MUDr. Eduard Minks Ph.D.
RECRUITING

Brno, South Moravian, 603 00, Czechia
MTZ Powered by Pratia
RECRUITING

Warsaw, Masovian Voivodeship, 02-172, Poland
Medicover Integrated Clinical Services (MICS) - Centrum Medyczne Bydgoszcz
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-065, Poland
Medsol Clinical Research Center
RECRUITING

Port Charlotte, Florida, 33952, United States
Michigan State University Clinical Center
RECRUITING

East Lansing, Michigan, 48824, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Mount Sinai Health System
RECRUITING

New York, New York, 10029, United States
Multi-profile Clinic "New Hospitals"
RECRUITING

Tbilisi, 0114, Georgia
NHO Sendai Medical Center
RECRUITING

Sendai, Miyagi, 983-8520, Japan
Nagoya City University Hospital
RECRUITING

Suita-shi, Osaka, 564-0013, Japan
National Hospital Organization - Nagoya Medical Center
RECRUITING

Nagoya, Aichi-ken, 460-0001, Japan
National Hospital Organization Niigata National Hospital
RECRUITING

Kashiwazaki-Shi, Niigata, 945-8585, Japan
National Hospital Organization Utano National Hospital
RECRUITING

Kyoto, 616-8255, Japan
Neurocentrum Bydgoszcz
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland
Neurologia Śląska Centrum Medyczne
RECRUITING

Katowice, Silesian Voivodeship, 40-123, Poland
Neurology Center of New England
RECRUITING

Foxborough, Massachusetts, 02035, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Niepubliczny Zakład Opieki Zdrowotnej NEURO - KARD
RECRUITING

Poznan, Greater Poland Voivodeship, 61-853, Poland
Okinawa National Hospital
RECRUITING

Ginowan-Shi, Okinawa, 901-2214, Japan
Pineo Medical Ecosystem
RECRUITING

Tbilisi, 0114, Georgia
Pseg Centro de Pesquisa Clinica
RECRUITING

São Paulo, 04038-002, Brazil
SFM Clinical Research
RECRUITING

Boca Raton, Florida, 33487, United States
STAT Research S.A.
RECRUITING

Ciudad Autónoma de Buenos Aires, Buenos Aires, C1023AAB, Argentina
Sapporo Medical University Hospital
RECRUITING

Sapporo, Hokkaido, 060-8543, Japan
Seirei Hamamatsu General Hospital
RECRUITING

Hamamatsu, Sizuoka [Shizuoka], 430-8558, Japan
Simon Khechinashvili University Hospital
RECRUITING

Tbilisi, 0179, Georgia
St. Marianna University Hospital
RECRUITING

Kawasaki, Kanagawa, 216-8511, Japan
Tokushima University Hospital
RECRUITING

Tokushima, Tokusima [Tokushima], 770-8503, Japan
Tokyo Medical University Hospital
RECRUITING

Shinjuku-ku, Tokyo, 160-0023, Japan
Toronto General Hospital
NOT_YET_RECRUITING

Toronto, Ontario, M5G 2C4, Canada
Townsville University Hospital
RECRUITING

Douglas, Queensland, 4814, Australia
Trinity Health - Grand Rapids Hospital
RECRUITING

Grand Rapids, Michigan, 49503, United States
Twoja Przychodnia Nowosolskie Centrum Medyczne
RECRUITING

Nowa Sól, Lubusz Voivodeship, 67-100, Poland
Universidade Estadual de Campinas
RECRUITING

Campinas, São Paulo, 13083-888, Brazil
Universitair Ziekenhuis (UZ) Leuven - Campus Gasthuisberg
RECRUITING

Leuven, Flemish Brabant, 3000, Belgium
University Hospital - London Health Sciences Centre
RECRUITING

London, Ontario, N6C 2R5, Canada
University of California Irvine
RECRUITING

Orange, California, 92868, United States
University of California San Francisco (UCSF)
RECRUITING

San Francisco, California, 94143, United States
University of Cincinnati Health Physicians - Clifton
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Kentucky
RECRUITING

Lexington, Kentucky, 40506, United States
University of Louisville Physicians
RECRUITING

Louisville, Kentucky, 40202, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
Uniwersyteckie Centrum Kliniczne w Gdańsku
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-214, Poland
Wellstar MCG Health Medical Center
RECRUITING

Augusta, Georgia, 30912, United States
Yokohama Medical Center
RECRUITING

Yokohama, Kanagawa, 245-8575, Japan

Conditions

Explore the condition pages connected to this study.

GENERALIZED MYASTHENIA GRAVIS