New drug aims to protect lungs in autoimmune patients

NCT ID NCT07495033

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This Phase 3 trial tests whether the drug telitacicept can slow the decline in lung function in people with connective tissue disease-related interstitial lung disease (CTD-ILD). About 260 adults with conditions like rheumatoid arthritis or lupus and confirmed lung scarring will receive either telitacicept or a placebo for 52 weeks. The main goal is to see if the drug helps preserve lung volume.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
telitacicept
What this could lead to
If successful, this could provide a new treatment option to slow lung damage in people with connective tissue disease-related lung disease.
What could go wrong
This is a Phase 3 trial, but results may not confirm benefit. The drug could cause side effects or fail to outperform placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CTD-ILD are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.