New drug aims to ease discomfort for ventilator patients in ICU
NCT ID NCT07372924
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new sedative called tegileridine fumarate in 120 ICU patients who need a breathing machine for at least two days. The goal is to see if it keeps patients comfortable and calm better than a standard sedative. Researchers will measure how often the drug works and check for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tegileridine fumarate injection
- What this could lead to
- If it works, this could provide a new option to keep ICU patients comfortable and calm while on a breathing machine.
- What could go wrong
- This is an early Phase 2 study with only 120 people, so results may not apply to everyone. The drug may not work better than existing sedatives or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGHubei, Wuhan, 430015, China
-
Zhongshan Hospital
RECRUITINGShanghai, Shanghai Municipality, 200030, China