New drug aims to ease discomfort for ventilator patients in ICU

NCT ID NCT07372924

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new sedative called tegileridine fumarate in 120 ICU patients who need a breathing machine for at least two days. The goal is to see if it keeps patients comfortable and calm better than a standard sedative. Researchers will measure how often the drug works and check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tegileridine fumarate injection

What this could lead to

If it works, this could provide a new option to keep ICU patients comfortable and calm while on a breathing machine.

What could go wrong

This is an early Phase 2 study with only 120 people, so results may not apply to everyone. The drug may not work better than existing sedatives or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Hubei, Wuhan, 430015, China

    Contact

  • Zhongshan Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

    Contact