Lung cancer patients get new hope with experimental combo therapy

NCT ID NCT04884282

First seen Feb 06, 2026 · Last updated May 12, 2026 · Updated 7 times

Summary

This study tests two drug combinations (Tedopi plus docetaxel or Tedopi plus nivolumab) as a second treatment option for people with advanced non-small-cell lung cancer whose cancer worsened after initial chemo-immunotherapy. About 105 adults with a specific genetic marker (HLA-A2+) will participate. The goal is to see if these combos improve survival compared to standard docetaxel alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AO Busto Arstizio PO Saronno

    Saronno, Varese, Italy

  • AOOR Papardo-Piemonte

    Messina, Italy

  • AOU "Maggiore della Carità"

    Novara, Italy

  • ASST Sette Laghi

    Varese, Italy

  • Azienda Ospedaliera di Perugia

    Perugia, Italy

  • Azienda Ospedaliero-Universitaria Careggi

    Florence, Italy

  • Centre Hospitalier de Cholet

    Cholet, 49300, France

  • Clinica Mi Tres Torres - UOMI Cancer Center

    Barcelona, 08017, Spain

  • Complejo Hospitalario Universitario A Coruña (CHUAC)

    A Coruña, 15006, Spain

  • GHR Mulhouse Sud Alsace - Hôpital Emile Muller

    Mulhouse, 68100, France

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Regional de Málaga - Hospital Civil

    Málaga, 29011, Spain

  • Hospital de Mataró

    Mataró, 08304, Spain

  • IRCCS - Arcispedale Santa Maria Nuova

    Reggio Emilia, Italy

  • Institut Sainte Catherine

    Avignon, 84918, France

  • Istituto Nazionale Tumori "Regina Elena"

    Roma, 00144, Italy

  • Istituto Oncologico Veneto

    Padova, 35128, Italy

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

    Meldola, Forlì, 47014, Italy

  • Nouvel Hôpital Civil - Hopitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • Ospedale Mater Salutis Legnago

    Legnago, Verona, 37045, Italy

  • Ospedale Sacro Cuore Don Calabria

    Negrar, Verona, Italy

  • Ospedale San Paolo

    Civitavecchia, Italy

  • Vall d'Hebron Universitary Hospital

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.