Engineered immune cells take aim at Hard-to-Treat KRAS cancers

NCT ID NCT07342738

First seen Jan 15, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This early-phase study tests a personalized cell therapy called TCR-T in 25 adults with advanced solid tumors (like colorectal or lung cancer) that have specific KRAS mutations and haven't responded to standard treatments. The therapy uses the patient's own immune cells, engineered to recognize and attack cancer cells carrying the KRAS mutation. The main goals are to check safety and see if the treatment can shrink tumors.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.