Engineered immune cells take on Hard-to-Treat KRAS cancers

NCT ID NCT07342738

First seen Jan 15, 2026 · Last updated Apr 28, 2026 · Updated 12 times

Summary

This early-phase study tests a personalized cell therapy (TCR-T) in 25 adults with advanced solid tumors caused by KRAS mutations, such as certain colorectal and lung cancers. The treatment involves collecting the patient's own immune cells, engineering them to better recognize and attack cancer, then infusing them back. The main goals are to check safety and see if tumors shrink or stabilize.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.