Engineered immune cells take on tough lymphoma

NCT ID NCT07473167

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment called TC011, which uses a patient's own immune cells engineered to find and attack lymphoma cells. It is for adults with large B-cell lymphoma that has come back or not responded to at least two prior treatments. The trial will check safety and how well the therapy works in 98 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TC011 (a type of CAR-T cell therapy that targets CD19 on cancer cells)

What this could lead to

If successful, this could offer a new treatment option for people with hard-to-treat large B-cell lymphoma that has not responded to standard chemotherapy.

What could go wrong

This is an early-phase trial (Phase 1/2) with only 98 participants, so results may not apply to everyone. CAR-T therapy can cause serious side effects like cytokine release syndrome and nervous system problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma primary mediastinal large B-cell lymphoma relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Seoul National University Hospital

    RECRUITING

    Seoul, Seoul, 03080, South Korea

    Contact