New hope for the toughest TB cases: 6-Month drug combo tested

NCT ID NCT02333799

Summary

This study tested a new combination of three drugs (bedaquiline, pretomanid, and linezolid) for people with severe, drug-resistant tuberculosis (TB) that other treatments couldn't cure. It involved 109 participants aged 14 and over and aimed to see if a shorter, 6-month treatment could effectively control the TB infection and prevent it from coming back. Researchers measured success by checking if the TB bacteria disappeared from participants' sputum and stayed gone after treatment ended.

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Contacts and locations

Locations

  • King DinuZulu Hospital Complex

    Sydenham, Durban, 4001, South Africa

  • Sizwe Tropical Disease Hospital

    Sandringham, Johannesburg, 2131, South Africa

  • Task Applied Science - Brooklyn Chest Hospital

    Ysterplaat, Cape Town, 7405, South Africa

Conditions

Explore the condition pages connected to this study.