New hope for rare cancer: tarlatamab takes on chemo in phase 3 trial
NCT ID NCT06937905
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial is testing whether the drug tarlatamab can help people with advanced neuroendocrine carcinoma live longer compared to standard chemotherapy. The study plans to enroll 129 participants who have already received prior treatment. Tarlatamab is given as an infusion every two weeks, while the chemotherapy options vary based on tumor type.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tarlatamab
What this could lead to
If it works, this could offer a new treatment option for people with advanced neuroendocrine carcinoma who have already tried other therapies.
What could go wrong
This is a Phase 3 trial, but it is still early to know if tarlatamab will work better than chemotherapy. Side effects, including immune reactions, are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Angers - CHU
RECRUITINGAngers, France
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Avignon - CH
RECRUITINGAvignon, France
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Besançon - CHU
RECRUITINGBesançon, France
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Bordeaux - CHU
RECRUITINGPessac, France
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Bordeaux - CHU
RECRUITINGPessac, France
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Boulogne - Ambroise Paré
RECRUITINGBoulogne, France
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Caen - CHU
RECRUITINGCaen, France
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Caen - CHU
RECRUITINGCaen, France
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Dijon - CHU Bocage
RECRUITINGDijon, France
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Dijon - Centre Georges-François Leclerc
RECRUITINGDijon, France
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Grenoble - CHU
RECRUITINGGrenoble, France
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Le Mans - CHG
RECRUITINGLe Mans, France
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Lille - Centre Oscar Lambret
RECRUITINGLille, France
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Limoges - CHU
RECRUITINGLimoges, France
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Limoges - CHU
RECRUITINGLimoges, France
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Lyon - Centre Léon Bérard
RECRUITINGLyon, France
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Lyon - HCL
RECRUITINGPierre-Bénite, France
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Lyon - Hôpital Edouard Herriot
RECRUITINGLyon, France
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Lyon - Hôpital Privé Jean Mermoz
RECRUITINGLyon, France
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Marseille - APHM
RECRUITINGMarseille, France
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Marseille - Institut Paoli-Calmettes
RECRUITINGMarseille, France
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Montpellier - CHU
RECRUITINGMontpellier, France
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Nantes - Hôpital Laennec
RECRUITINGSaint-Herblain, France
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Nantes - Institut de Cancérologie de l'Ouest
RECRUITINGSaint-Herblain, France
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Nice - Centre Antoine Lacassagne
RECRUITINGNice, France
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Paris - Curie
RECRUITINGParis, France
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Paris - Hôpital Cochin
RECRUITINGParis, France
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Paris - Saint-Antoine
RECRUITINGParis, France
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Paris - Tenon
RECRUITINGParis, France
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Poitiers - CHU
RECRUITINGPoitiers, France
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Reims - CHU
RECRUITINGReims, France
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Rennes - CHU
RECRUITINGRennes, France
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Rouen - CHU
RECRUITINGRouen, France
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Strasbourg - Nouvel Hôpital Civil
RECRUITINGStrasbourg, France
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Toulon - CHI
RECRUITINGToulon, France
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Toulouse - CHU
RECRUITINGToulouse, France
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Tours - CHU
RECRUITINGChambray-lès-Tours, France
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Tours - CHU
RECRUITINGTours, France
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Vandoeuvre-lès-Nancy - Institut de Cancérologie de Lorraine
RECRUITINGVandœuvre-lès-Nancy, France
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Villefranche sur Saône - CH
RECRUITINGVillefranche-sur-Saône, France
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