New hope for rare cancer: tarlatamab takes on chemo in phase 3 trial
NCT ID NCT06937905
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial is testing whether the drug tarlatamab can help people with advanced neuroendocrine carcinoma live longer compared to standard chemotherapy. The study plans to enroll 129 participants who have already received prior treatment. Tarlatamab is given as an infusion every two weeks, while the chemotherapy options vary based on tumor type.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tarlatamab
- What this could lead to
- If it works, this could offer a new treatment option for people with advanced neuroendocrine carcinoma who have already tried other therapies.
- What could go wrong
- This is a Phase 3 trial, but it is still early to know if tarlatamab will work better than chemotherapy. Side effects, including immune reactions, are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Angers - CHU
RECRUITINGAngers, France
Contact Email: •••••@•••••
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Avignon - CH
RECRUITINGAvignon, France
Contact Email: •••••@•••••
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Besançon - CHU
RECRUITINGBesançon, France
Contact Email: •••••@•••••
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Bordeaux - CHU
RECRUITINGPessac, France
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Bordeaux - CHU
RECRUITINGPessac, France
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Boulogne - Ambroise Paré
RECRUITINGBoulogne, France
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Caen - CHU
RECRUITINGCaen, France
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Caen - CHU
RECRUITINGCaen, France
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Dijon - CHU Bocage
RECRUITINGDijon, France
Contact Email: •••••@•••••
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Dijon - Centre Georges-François Leclerc
RECRUITINGDijon, France
Contact Email: •••••@•••••
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Grenoble - CHU
RECRUITINGGrenoble, France
Contact Email: •••••@•••••
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Le Mans - CHG
RECRUITINGLe Mans, France
Contact Email: •••••@•••••
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Lille - Centre Oscar Lambret
RECRUITINGLille, France
Contact Email: •••••@•••••
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Limoges - CHU
RECRUITINGLimoges, France
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Limoges - CHU
RECRUITINGLimoges, France
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Lyon - Centre Léon Bérard
RECRUITINGLyon, France
Contact Email: •••••@•••••
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Lyon - HCL
RECRUITINGPierre-Bénite, France
Contact Email: •••••@•••••
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Lyon - Hôpital Edouard Herriot
RECRUITINGLyon, France
Contact Email: •••••@•••••
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Lyon - Hôpital Privé Jean Mermoz
RECRUITINGLyon, France
Contact Email: •••••@•••••
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Marseille - APHM
RECRUITINGMarseille, France
Contact Email: •••••@•••••
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Marseille - Institut Paoli-Calmettes
RECRUITINGMarseille, France
Contact Email: •••••@•••••
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Montpellier - CHU
RECRUITINGMontpellier, France
Contact Email: •••••@•••••
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Nantes - Hôpital Laennec
RECRUITINGSaint-Herblain, France
Contact Email: •••••@•••••
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Nantes - Institut de Cancérologie de l'Ouest
RECRUITINGSaint-Herblain, France
Contact Email: •••••@•••••
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Nice - Centre Antoine Lacassagne
RECRUITINGNice, France
Contact Email: •••••@•••••
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Paris - Curie
RECRUITINGParis, France
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Paris - Hôpital Cochin
RECRUITINGParis, France
Contact Email: •••••@•••••
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Paris - Saint-Antoine
RECRUITINGParis, France
Contact Email: •••••@•••••
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Paris - Tenon
RECRUITINGParis, France
Contact Email: •••••@•••••
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Poitiers - CHU
RECRUITINGPoitiers, France
Contact Email: •••••@•••••
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Reims - CHU
RECRUITINGReims, France
Contact Email: •••••@•••••
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Rennes - CHU
RECRUITINGRennes, France
Contact Email: •••••@•••••
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Rouen - CHU
RECRUITINGRouen, France
Contact Email: •••••@•••••
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Strasbourg - Nouvel Hôpital Civil
RECRUITINGStrasbourg, France
Contact Email: •••••@•••••
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Toulon - CHI
RECRUITINGToulon, France
Contact Email: •••••@•••••
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Toulouse - CHU
RECRUITINGToulouse, France
Contact Email: •••••@•••••
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Tours - CHU
RECRUITINGChambray-lès-Tours, France
Contact Email: •••••@•••••
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Tours - CHU
RECRUITINGTours, France
Contact Email: •••••@•••••
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Vandoeuvre-lès-Nancy - Institut de Cancérologie de Lorraine
RECRUITINGVandœuvre-lès-Nancy, France
Contact Email: •••••@•••••
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Villefranche sur Saône - CH
RECRUITINGVillefranche-sur-Saône, France
Contact Email: •••••@•••••
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