New hope for kids with inoperable brain cancer: targeted radiation trial seeks to control tumors

NCT ID NCT05610891

Summary

This early-stage study is testing a new targeted radiation drug called CLR 131 in children and young adults (ages 10-25) with aggressive brain tumors that have returned or not responded to other treatments and cannot be removed by surgery. The main goals are to find a safe and effective dose and to see if the treatment can help control the cancer and extend life. This is a Phase 1 trial focused on safety and finding the right dose for future studies.

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Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Stanford University

    Palo Alto, California, 94304, United States

  • Texas Children's Cancer Center, Baylor College of Medicine

    Houston, Texas, 77030, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Wisconsin, Carbone Cancer Center

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.