New cream could help kids with psoriasis

NCT ID NCT05172726

Ongoing Disease control Sponsor: Organon and Co Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a cream called tapinarof for children aged 2 to 17 with plaque psoriasis, a skin condition causing red, scaly patches. The cream is applied once daily to see if it is safe and tolerable. About 58 children will take part in this open-label trial, meaning everyone knows they are getting the active cream.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tapinarof cream, 1%
What this could lead to: If successful, this could provide a new topical treatment option for children with plaque psoriasis, potentially improving symptom control.
What could go wrong: This is an early-phase, open-label study with only 58 participants, so results may not confirm effectiveness or safety for all children. Side effects like skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLAQUE PSORIASIS

Contacts and locations

Locations

Alliance Clinical Trials

Waterloo, Ontario, N2J 1C4, Canada
Dawes Fretzin Clinical Research Group

Indianapolis, Indiana, 46250, United States
Dermatology Research Institute Inc.

Calgary, Alberta, T2J7E1, Canada
Dermatology Specialists of Spokane

Spokane, Washington, 99202, United States
First OC Dermatology

Fountain Valley, California, 92708, United States
Innovaderm Research, Inc.

Montreal, Quebec, H2X 2V1, Canada
Lynderm Research Inc.

Markham, Ontario, L3P1X3, Canada
Mission Dermatology Center

Rancho Santa Margarita, California, 92688, United States
Northwest Arkansas Clinical Trials Center, PLLC

Rogers, Arkansas, 72758, United States
Northwestern University Feinberg School of Medicine

Chicago, Illinois, 60611, United States
Olympian Clinical Research

Tampa, Florida, 33615, United States
Options Research Group

West Lafayette, Indiana, 47906, United States
Oregon Dermatology & Research Center

Portland, Oregon, 97210, United States
RM Medical Research

Miami Lakes, Florida, 33014, United States
Rejuvenation Laser Dermatology Clinics

Edmonton, Alberta, T5J3S9, Canada
San Marcus Research Clinic, Inc.

Miami Lakes, Florida, 33014, United States
Skincare Studio INC

St. John's, Newfoundland and Labrador, A1E1V4, Canada
Whitby Health Centre Dermatology Trials

Whitby, Ontario, L1P0P9, Canada
Wright State Physicians Pharmacology Translational Unit

Fairborn, Ohio, 45324, United States

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