New cream could help kids with psoriasis

NCT ID NCT05172726

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a cream called tapinarof for children aged 2 to 17 with plaque psoriasis, a skin condition causing red, scaly patches. The cream is applied once daily to see if it is safe and tolerable. About 58 children will take part in this open-label trial, meaning everyone knows they are getting the active cream.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tapinarof cream, 1%

What this could lead to

If successful, this could provide a new topical treatment option for children with plaque psoriasis, potentially improving symptom control.

What could go wrong

This is an early-phase, open-label study with only 58 participants, so results may not confirm effectiveness or safety for all children. Side effects like skin irritation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alliance Clinical Trials

    Waterloo, Ontario, N2J 1C4, Canada

  • Dawes Fretzin Clinical Research Group

    Indianapolis, Indiana, 46250, United States

  • Dermatology Research Institute Inc.

    Calgary, Alberta, T2J7E1, Canada

  • Dermatology Specialists of Spokane

    Spokane, Washington, 99202, United States

  • First OC Dermatology

    Fountain Valley, California, 92708, United States

  • Innovaderm Research, Inc.

    Montreal, Quebec, H2X 2V1, Canada

  • Lynderm Research Inc.

    Markham, Ontario, L3P1X3, Canada

  • Mission Dermatology Center

    Rancho Santa Margarita, California, 92688, United States

  • Northwest Arkansas Clinical Trials Center, PLLC

    Rogers, Arkansas, 72758, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

  • Olympian Clinical Research

    Tampa, Florida, 33615, United States

  • Options Research Group

    West Lafayette, Indiana, 47906, United States

  • Oregon Dermatology & Research Center

    Portland, Oregon, 97210, United States

  • RM Medical Research

    Miami Lakes, Florida, 33014, United States

  • Rejuvenation Laser Dermatology Clinics

    Edmonton, Alberta, T5J3S9, Canada

  • San Marcus Research Clinic, Inc.

    Miami Lakes, Florida, 33014, United States

  • Skincare Studio INC

    St. John's, Newfoundland and Labrador, A1E1V4, Canada

  • Whitby Health Centre Dermatology Trials

    Whitby, Ontario, L1P0P9, Canada

  • Wright State Physicians Pharmacology Translational Unit

    Fairborn, Ohio, 45324, United States