Could a common ADHD drug help Parkinson's patients walk better?
NCT ID NCT02879136
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested whether adding a low dose of methylphenidate (Ritalin) or atomoxetine (Strattera) to standard physical therapy improves gait and balance in people with Parkinson's disease more than physical therapy alone. 23 participants were randomly assigned to one of the two drugs plus therapy, or therapy alone. The study measured changes in balance and walking speed over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- methylphenidate (Ritalin) and atomoxetine (Strattera)
- What this could lead to
- If it works, this could point toward a way to improve walking and balance in Parkinson's disease by combining medication with physical therapy.
- What could go wrong
- This is a very early pilot study with only 23 people, so results may not apply widely. The medications can cause side effects like increased heart rate or anxiety, and the combination may not work better than therapy alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States