Could a common ADHD drug help Parkinson's patients walk better?

NCT ID NCT02879136

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether adding a low dose of methylphenidate (Ritalin) or atomoxetine (Strattera) to standard physical therapy improves gait and balance in people with Parkinson's disease more than physical therapy alone. 23 participants were randomly assigned to one of the two drugs plus therapy, or therapy alone. The study measured changes in balance and walking speed over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

methylphenidate (Ritalin) and atomoxetine (Strattera)

What this could lead to

If it works, this could point toward a way to improve walking and balance in Parkinson's disease by combining medication with physical therapy.

What could go wrong

This is a very early pilot study with only 23 people, so results may not apply widely. The medications can cause side effects like increased heart rate or anxiety, and the combination may not work better than therapy alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States