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New hope for rare blood cancer: drug combo aims for remission

NCT ID NCT07007052

Not yet recruiting Disease control Sponsor: French Innovative Leukemia Organisation Source: ClinicalTrials.gov ↗

First seen Nov 26, 2025 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tests a combination of two drugs, tagraxofusp and venetoclax, in adults with a rare and aggressive blood cancer called BPDCN who have not yet been treated. The main goal is to see if this combo can make the cancer disappear or shrink significantly after three months. Patients will receive the drugs in cycles, and depending on how well they respond, they may continue treatment, get a stem cell transplant, or stop if it doesn't work.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AMIENS - CH Amiens Picardie Site Sud

    Amiens, 80054, France

  • ANGERS - CHU - Maladies du sang

    Angers, 49933, France

  • AP-HP - Hôpital Necker

    Paris, 75015, France

  • AP-HP- CRETEIL - CHU Henri Mondor

    Créteil, 94000, France

  • APHP - HOPITAL COCHIN - Hématologie

    Paris, 75014, France

  • APHP - Hôpital Saint-Louis - Hématologie adultes

    Paris, 75010, France

  • ARGENTEUIL - Centre hospitalier Victor Dupouy

    Argenteuil, France

  • AVIGNON - Centre Hospitalier

    Avignon, 84000, France

  • BESANCON - Hôpital Jean Minjoz - Hématologie

    Besançon, 25030, France

  • BORDEAUX - Hôpital Haut-Levêque

    Pessac, 33600, France

  • CHU SAINT-ETIENNE - iCHUSE

    Saint-Etienne, 42271, France

  • CLAMART - Hôpital d'Instruction des Armées de Percy

    Clamart, 92140, France

  • Clermont-Ferrand - Chu Estaing

    Clermont-Ferrand, 63000, France

  • Corbeil-Essonnes - Ch Sud Francilien

    Corbeil-Essonnes, France

  • Grenoble CHU - Hématologie Clinique

    Grenoble, 38043, France

  • LILLE CHU - Hôpital Claude Huriez

    Lille, 59037, France

  • LYON HCL- Site Sud

    Lyon, France

  • Limoges CHU

    Limoges, France

  • MARSEILLE - Institut Paoli-Calmettes

    Marseille, 13000, France

  • METZ - CHR Metz-Thionville

    Metz, 57085, France

  • MULHOUSE GHRMSA - Hôpital E. Muller - Hématologie

    Mulhouse, 68070, France

  • Montpellier - Chu Saint Eloi

    Montpellier, France

  • NANCY - CHU de Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • NANTES - Hôpital Hôtel Dieu - Hématologie Clinique

    Nantes, 44093, France

  • Nimes CHU

    Nîmes, France

  • POITIERS - Hôpital La Milétrie - Hématologie Clinique

    Poitiers, 86000, France

  • REIMS - Hôpital Robert Debré - Hématologie Clinique

    Reims, 51100, France

  • RENNES - CHU Pontchaillou - Hématologie Clinique

    Rennes, 35033, France

  • ROUEN - Centre Henri Becquerel - Service Hématologie Clinique

    Rouen, 76038, France

  • Strasbourg - Institut de Cancerologie Strasbourg

    Strasbourg, 67200, France

  • TOURS - Hôpital Bretonneau

    Tours, 37000, France

  • Toulouse - IUCT Oncopole - Service d'Hématologie

    Toulouse, France

  • VERSAILLES - Hôpital André Mignot

    Versailles, France

  • Villejuif Igr - Gustave Roussy

    Villejuif, 94804, France

Conditions

Explore the condition pages connected to this study.

BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM (BPDCN) BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM (BPDCN)